Fay Springer Handbook of Auditory Research continued from page ii Volume 22: Evolution of the Vertebrate Auditory System Edited by Geoffrey A. Rybak, Talaska, and Schacht summarize the latest on drug-inducedhearing loss in Chapter 8. Talaska, and Jochen Schacht 9. Fay Volume 3: Human Psychophysics Edited by William Yost, Arthur N. The current volume thus builds on and expands the information presented in earlier volumes of the Handbook of Auditory Research. The E-mail message field is required.
Apoptosis is an orderly 1. While the challenges to resolve mechanisms of auditory trauma, design protection and accomplish repair are formidable, they are not—giventime and resources—insurmountable. Fay Volume 14: Genetics and Auditory Disorders Edited by Bronya J. Extending the chapter on genetics from a physiological perspective, Wangemann in Chapter 3 treats disorders of the cochlea with the background of our understanding of cellular metabolism and metabolic regulation. Schacht Even though we lack detailed knowledge of some of the basic pathological mechanisms, the next decade will likely see effective pharmacological protection against a number of the disorders that are discussed in this volume.
In particular the authors address the major entities of peripheral auditory trauma, discuss the underlying mechanisms, the central nervous system consequences, protective interventions and finally explore the possibilities to restore cochlear morphology and function. In addition to a detailed consideration of cell death pathways, the authors outline the state-of-the-artattempts to protect the cochlea against environmental insults, with special attention to the spiral ganglion neurons. Other volumes in the series deal with topics that have begun to mature more recently, such as development, plasticity, and computational models of neural processing. During the last three decades, autoimmune inner ear disease has not only gained recognition as a genuine inner ear disorder but has also been an expanding subject of experimental research. Prompted by his partial deafness and tinnitus, Townshend supported the formation of the advocacy group H. Tinnitus: Theories, Mechanisms, and Treatments. Popper Volume 18: Speech Processing in the Auditory System Edited by Steven Greenberg, William Ainsworth, Arthur N.
Thus, genetic hearing loss may become amenable to intervention based on success in correcting hearing function in mouse models Probst et al. Another event was the epidemic of German measles that hit the United States in the early 1960s and brought with it deafness in newborns. Fay Volume 8: The Cochlea Edited by Peter Dallos, Arthur N. In the broadest sense, all auditory pathologies are disorders of cellular homeostasis. In the broadest sense, all auditory pathologies are disorders of cellular homeostasis. Fay Volume 13: Comparative Hearing: Birds and Reptiles Edited by Robert Dooling, Arthur N. Frisina The Patterns and Mechanisms of Noise-Induced Cochlear Pathology Donald Henderson, Bohua Hu, and Eric Bielefeld Drug-Induced Hearing Loss Leonard P.
The resulting public health campaign for vaccinations became a source of popular knowledge about disabilities. Morest and Potashner further detail the pathophysiology of central auditory pathways and its molecular basis in Chapter 9. Fay Volume 2: The Mammalian Auditory Pathway: Neurophysiology Edited by Arthur N. In vivo experimentation, although tedious, time consuming, and costly, will remain indispensable in studying most pathologies and will remain the ultimate test before any treatment can be translated into the clinic. Such a treatment may be integrated into cochlear implants that then serve both the delivery of sound sensation and survival or regenerative factors.
The initial death throes of a cell are balanced by attempts at restoring homeostasis until one outweighs the other. One of the first was the arrival of chemotherapy and, in particular, the discovery and therapeutic application of aminoglycoside antibiotics Schatz et al. Two themes run through the chapters in this book: cellular homeostasis and cell death. Tinnitus, a major enigma among hearing disorders, is the topic of Chapter 4. Auditory Trauma, Protection and Repair presents recent developments in auditory research and their potential translation to the clinical setting.
Fay is Director of the Parmly Hearing Institute and Professor of Psychology at Loyola University of Chicago. Fay Volume 24: Pitch: Neural Coding and Perception Edited by Christopher J. Popper is Professor in the Department of Biology and Co-Director of the Center for Comparative and Evolutionary Biology of Hearing at the University of Maryland, College Park. Fay Volume 31: Auditory Trauma, Protection, and Repair Edited by Jochen Schacht, Arthur N. Even in dying, the cell attempts to contain the damage to surrounding partners and preferably invokes apoptosis. The immune response in the inner ear, which can be beneficial in protecting from invading pathogens, can cause specific 4 J.
Register a Free 1 month Trial Account. In particular the authors address the major entities of peripheral auditory trauma, discuss the underlying mechanisms, the central nervous system consequences, protective interventions and finally explore the possibilities to restore cochlear morphology and function. The past decade has brought great advances in our understanding of the mechanisms underlying auditory pathologies. Likewise drug-exposedand, in particular, aging hair cells die over an extended period of time, and it remains to be seen how attempts at rescue can capitalize on such delayed time courses of cell death. Auditory pathologies resulting from noise or drugs have long been established. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. About the series: The Springer Handbook of Auditory Research presents a series of synthetic reviews of fundamental topics dealing with auditory systems.